Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544006 | 1.00 | SCN9A (0.53) | SCN9AKMT2ACTSSCTSLCTSB | |
| SCHEMBL9544975 | 0.90 | CTSK (0.51) | SCN9ACTSSCTSKATMACE | |
| SCHEMBL9544256 | 0.90 | CTSK (0.51) | SCN9ACTSSCTSKATMACE | |
| SCHEMBL9544328 | 0.88 | MAPK1 (0.49) | SCN9AKMT2AMAPK1 | |
| SCHEMBL9544331 | 0.88 | MAPK1 (0.49) | SCN9AKMT2AMAPK1 | |
| SCHEMBL9544867 | 0.80 | CTSK (0.48) | SCN9ACTSSCTSKACE | |
| SCHEMBL9543839 | 0.78 | ACE (0.43) | ACE | |
| SCHEMBL6164761 | 0.78 | KMT2A (0.60) | SCN9AKMT2ACTSSCTSLCTSB | |
| SCHEMBL8244870 | 0.78 | KMT2A (0.60) | SCN9AKMT2ACTSSCTSLCTSB | |
| SCHEMBL9544221 | 0.78 | CTSS (0.46) | SCN9ACTSSCTSLCTSKACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |