Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544256 | 0.86 | CTSK (0.51) | CTSSCTSKSCN9AACE | |
| SCHEMBL9544975 | 0.86 | CTSK (0.51) | CTSSCTSKSCN9AACE | |
| SCHEMBL9544867 | 0.83 | CTSK (0.48) | CTSSCTSKSCN9AACE | |
| SCHEMBL9543489 | 0.82 | CCKBR (0.48) | CTSSCTSL | |
| SCHEMBL9544006 | 0.78 | SCN9A (0.53) | CTSSCTSKSCN9ACTSLACE | |
| SCHEMBL9544014 | 0.78 | SCN9A (0.53) | CTSSCTSKSCN9ACTSLACE | |
| SCHEMBL9543252 | 0.76 | CXCR3 (0.51) | CTSSCTSKITGB3ITGA2BACE | |
| SCHEMBL9543839 | 0.76 | ACE (0.43) | ACE | |
| SCHEMBL8834681 | 0.75 | KLK5 (0.51) | KLK7KLK5CTSLACE | |
| SCHEMBL9543250 | 0.75 | ACE (0.51) | CTSSCTSKACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |