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Sugi Predict / Compounds / 2-Phenylbenzo[D]Oxazole

2-Phenylbenzo[D]Oxazole

2-Phenylbenzo[D]Oxazole

SCHEMBL9544026

CC(=O)n1nc2ccccc2c1Br.c1ccc(-c2nc3ccccc3o2)cc1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.50
▸ RAB9A P51151 4/20 0.50
▸ KDM4E B2RXH2 7/20 0.47
▸ HSD17B10 Q99714 5/20 0.47
▸ ALDH1A1 P00352 5/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ HPGD P15428 3/20 0.47
▸ MAPT P10636 2/20 0.47
▸ POLB P06746 2/20 0.46
▸ CASP3 P42574 1/20 0.46
▸ SENP8 Q96LD8 1/20 0.46
▸ SENP7 Q9BQF6 1/20 0.46
▸ SENP6 Q9GZR1 1/20 0.46
▸ USP2 O75604 2/20 0.45
▸ ELANE P08246 1/20 0.44
▸ HDAC6 Q9UBN7 1/20 0.44
▸ MTNR1A P48039 1/20 0.43
▸ MTNR1B P49286 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127188 0.81 ELANE (0.43) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL5462415 0.79 RAB9A (0.68) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL11136013 0.75 NPC1 (0.66) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL31738605 0.73 NPC1 (0.72) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL29767802 0.73 NPC1 (0.72) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL2458370 0.73 NPC1 (0.72) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL27567766 0.73 NPC1 (0.72) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL29819732 0.73 NPC1 (0.72) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL127448 0.73 NPC1 (0.72) NPC1RAB9AKDM4EHSD17B10ALDH1A1
2-Phenylbenzo[D]Oxazole SCHEMBL395084 0.73 NPC1 (0.72) NPC1RAB9AKDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993010753-A1 UVA-ABSORBING SUNSCREEN METAL COMPLEXES RICHARDSON-VICKS, INC. (US) 1993-06-10 — — WO disclosed