SCHEMBL127188

SCHEMBL127188

CC(=O)n1nc2ccccc2c1Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.43
RAB9A P51151 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 1/20 0.41
NR1H2 P55055 3/20 0.40
NR1H3 Q13133 3/20 0.40
POLB P06746 3/20 0.40
PDGFRA P16234 1/20 0.40
CDK5 Q00535 1/20 0.40
TYRO3 Q06418 1/20 0.40
TP53 P04637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 5/20 0.38
GAA P10253 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
GLA P06280 3/20 0.38
PDE10A Q9Y233 1/20 0.38
CXCR3 P49682 1/20 0.37
ADORA3 P0DMS8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylbenzo[D]Oxazole SCHEMBL9544026 0.81 NPC1 (0.50) ELANERAB9ANPC1POLBTP53
SCHEMBL5583818 0.71 ELANE (0.54) ELANERAB9AL3MBTL1NPC1NR1H2
SCHEMBL17831574 0.71 MPO (0.42) HSD17B10KDM4EGAAALDH1A1HPGD
SCHEMBL5763004 0.68 MPO (0.46) L3MBTL1NPC1NR1H2NR1H3TP53
SCHEMBL8304178 0.68 ELANE (0.54) ELANERAB9AL3MBTL1NPC1POLB
SCHEMBL27971365 0.68 ELANE (0.54) ELANERAB9AL3MBTL1NPC1NR1H2
SCHEMBL28283327 0.67 MPO (0.60) POLBKDM4EGAAALDH1A1HPGD
SCHEMBL8143932 0.66 NPC1 (0.44) ELANERAB9AL3MBTL1NPC1NR1H2
SCHEMBL11752876 0.66 TSHR (0.47) ELANEL3MBTL1NPC1POLBHSD17B10
SCHEMBL4684902 0.66 HDAC8 (0.44) ELANERAB9AL3MBTL1NPC1PDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3164196-B1 TOPICAL FORMULATIONS FOR UV PROTECTION TOPGENIX INC (US) 2021-08-18 EP claimed
EP-3164196-A1 TOPICAL FORMULATIONS FOR UV PROTECTION TOPGENIX, INC. (US) 2017-05-10 EP claimed
US-20170119641-A1 TOPICAL FORMULATIONS FOR UV PROTECTION TopGeniX, Inc. 2017-05-04 US claimed
WO-2015195546-A1 TOPICAL FORMULATIONS FOR UV PROTECTION TopGeniX, Inc. (US) 2015-12-23 WO claimed
EP-2916814-A1 COMPOSITION CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN Colabs International Corporation (US) 2015-09-16 EP claimed
WO-2014074555-A1 COMPOSITION CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN CoLabs International Corporation (US) 2014-05-15 WO claimed
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen CoLabs International Corporation (US) 2014-05-08 US claimed
CN-102245643-A Cosmetic composition containing acetylated oligoglucuronans SEDERMA SA 2011-11-16 CN claimed
EP-2367852-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS Sederma (FR) 2011-09-28 EP claimed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 US claimed
WO-2010067327-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS SEDERMA (FR) 2010-06-17 WO claimed
WO-2010044076-A2 COSMETIC AND TOPICAL USE OF XANTHOHUMOL INCLUDING BRIGHTENING SKIN COMPLEXION AND REDUCING CUTANEOUS REDNESS SEDERMA (FR) 2010-04-22 WO claimed
EP-1924254-A2 USE OF TELLURIUM COMPOUNDS FOR PROTECTION FROM ULTRA-VIOLET RADIATION Biomas Ltd. (IL) 2008-05-28 EP claimed
WO-2007032010-A2 USE OF TELLURIUM COMPOUNDS FOR PROTECTION FROM ULTRA-VIOLET RADIATION BIOMAS LTD. (IL) 2007-03-22 WO claimed
US-20060193789-A1 Surfacant, film forming agent, water, gas propellant; plant and animal extracts and oils; may include malathion FOAMIX LTD. (IL) 2006-08-31 US claimed
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2005-08-25 US claimed
US-20260091073-A1 COMPOSITIONS CONTAINING SILYMARIN AND SULFOALKYL ETHER CYCLODEXTRIN AND METHODS OF USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2026-04-02 US disclosed
US-12589057-B2 Cosmetic composition of liquid crystal lipid particles for personal care applications BASF SE (DE) 2026-03-31 US disclosed
US-4098881-A COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES THE PROCTER & GAMBLE COMPANY (US) 1978-07-04 US disclosed
US-4009254-A UNSYMMETRICAL ETHERS; SUNSCREEN AGENTS COLGATE-PALMOLIVE COMPANY (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 ELANE 2895/4885RAB9A 3608/4885L3MBTL1 3145/4885
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen MSH6, TYR, CUTA ELANE 1317/4885RAB9A 3568/4885L3MBTL1 4831/4885
US-20170119641-A1 TOPICAL FORMULATIONS FOR UV PROTECTION ERCC4, ERCC1, UNG ELANE 395/4885RAB9A 1217/4885L3MBTL1 4347/4885
US-12589057-B2 Cosmetic composition of liquid crystal lipid particles for personal care applications DSG1, H1-10, DSC1 ELANE 232/4885RAB9A 355/4885L3MBTL1 1524/4885
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 ELANE 2895/4885RAB9A 3608/4885L3MBTL1 3145/4885
US-20260091073-A1 COMPOSITIONS CONTAINING SILYMARIN AND SULFOALKYL ETHER CYCLODEXTRIN AND METHODS OF USING THE SAME GYS2, COL1A1, COL14A1 ELANE 2543/4885RAB9A 1189/4885L3MBTL1 1705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.