Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544272 | 1.00 | CTSK (0.52) | CTSKCTSLCTSBMAPK1MAPT | |
| SCHEMBL2374657 | 0.86 | SCN9A (0.61) | CTSKCTSLCTSBMAPK1MAPT | |
| SCHEMBL2374682 | 0.86 | SCN9A (0.61) | CTSKCTSLCTSBMAPK1MAPT | |
| SCHEMBL9543251 | 0.85 | CTSK (0.65) | CTSKCTSLCTSBMAPTSCN9A | |
| SCHEMBL9545318 | 0.84 | CTSK (0.54) | CTSKCTSLCTSBMAPK1MAPT | |
| SCHEMBL9544088 | 0.84 | CTSL (0.64) | CTSKCTSLMAPT | |
| SCHEMBL28261719 | 0.83 | MAPT (0.66) | CTSKCTSLCTSBMAPK1MAPT | |
| SCHEMBL28261718 | 0.83 | MAPT (0.66) | CTSKCTSLCTSBMAPK1MAPT | |
| SCHEMBL10270538 | 0.81 | CTSC (0.58) | CTSKCTSLCTSBMAPTNPSR1 | |
| SCHEMBL29922866 | 0.80 | FPR2 (0.64) | CTSKCTSLCTSBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |