Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 9/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543316 | 0.89 | CTSK (0.50) | CTSKCTSSCXCR3 | |
| SCHEMBL9544975 | 0.86 | CTSK (0.51) | CTSKCTSSACESCN9AATM | |
| SCHEMBL9544256 | 0.86 | CTSK (0.51) | CTSKCTSSACESCN9AATM | |
| SCHEMBL9542908 | 0.84 | ACE (0.45) | ACEABCB11HDAC8 | |
| SCHEMBL9544239 | 0.84 | SYK (0.48) | CTSSCXCR3ATM | |
| SCHEMBL9544802 | 0.84 | ACE (0.46) | CXCR3ACEABCB11 | |
| SCHEMBL9543837 | 0.83 | ELANE (0.47) | CXCR3ATM | |
| SCHEMBL9544283 | 0.82 | KMT2A (0.43) | CXCR3ATM | |
| SCHEMBL9544282 | 0.82 | KMT2A (0.43) | CXCR3ATM | |
| SCHEMBL9544085 | 0.82 | CTSS (0.48) | CTSKCTSSCXCR3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |