Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.66 |
| ▸ | YAP1 | P46937 | 3/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308698 | 0.90 | GPR119 (0.63) | GPR119YAP1ITGB3ITGA2BFAAH | |
| SCHEMBL7972834 | 0.89 | GPR119 (0.65) | GPR119YAP1ITGB3ITGA2B | |
| SCHEMBL7972831 | 0.89 | GPR119 (0.65) | GPR119YAP1ITGB3ITGA2B | |
| SCHEMBL7312363 | 0.87 | GPR119 (0.62) | GPR119YAP1ITGB3ITGA2B | |
| SCHEMBL7315022 | 0.85 | GPR119 (0.64) | GPR119YAP1FAAH | |
| SCHEMBL25802282 | 0.85 | GPR119 (0.64) | GPR119YAP1ITGB3ITGA2BFAAH | |
| SCHEMBL7313782 | 0.84 | YAP1 (0.63) | GPR119YAP1ITGB3ITGA2B | |
| SCHEMBL7280692 | 0.83 | GPR119 (0.62) | GPR119YAP1ITGB3ITGA2BFAAH | |
| SCHEMBL7281055 | 0.83 | ITGB3 (0.71) | GPR119YAP1ITGB3ITGA2B | |
| SCHEMBL1924373 | 0.82 | GPR119 (0.70) | GPR119YAP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016697-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1993-09-02 | — | — | WO | disclosed |