Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541888 | 0.83 | SHBG (0.47) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL3754970 | 0.82 | SHBG (0.44) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL9464776 | 0.82 | CYP17A1 (0.53) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL14285029 | 0.81 | PGR (0.57) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL14318945 | 0.81 | PGR (0.57) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL3366869 | 0.80 | CYP19A1 (0.65) | SHBGNR3C1ALDH1A1PGRLMNA | |
| SCHEMBL9544771 | 0.79 | SHBG (0.43) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL9542667 | 0.79 | SHBG (0.43) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| Methyltestosterone SCHEMBL6472960 | 0.79 | SHBG (1.00) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| Methyltestosterone SCHEMBL4442874 | 0.79 | SHBG (1.00) | SHBGNR3C1ALDH1A1PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |