Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9038127 | 0.85 | MAPT (0.39) | TDP1TSHRL3MBTL1CYP3A4MAPT | |
| SCHEMBL956511 | 0.80 | CES1 (0.50) | TDP1TSHRL3MBTL1CYP3A4MAPT | |
| SCHEMBL64274 | 0.80 | TDP1 (0.52) | TDP1TSHRL3MBTL1CYP3A4MAPT | |
| SCHEMBL3720381 | 0.80 | TDP1 (0.52) | TDP1TSHRL3MBTL1CYP3A4MAPT | |
| SCHEMBL2362058 | 0.78 | TDP1 (0.50) | TDP1TSHRL3MBTL1CYP3A4MAPT | |
| SCHEMBL18690253 | 0.78 | CES1 (0.48) | TDP1TSHRL3MBTL1CYP3A4MAPT | |
| SCHEMBL7202702 | 0.77 | TSHR (0.50) | TDP1TSHRL3MBTL1CYP3A4MAPT | |
| SCHEMBL2351713 | 0.76 | HSD11B1 (0.52) | TSHRMAPTPOLBRECQLCES1 | |
| SCHEMBL1023729 | 0.76 | TDP1 (0.48) | TDP1TSHRL3MBTL1CYP3A4MAPT | |
| SCHEMBL2146344 | 0.76 | TDP1 (0.48) | TDP1TSHRL3MBTL1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397420-B | 3- (5- aryl-1,3,4-oxdiazole -2- bases) asarinin analog derivative, preparation method and application | 郑州大学 | 2018-10-09 | — | — | CN | claimed |
| CN-105669551-B | 7 benzo (c) acridines are to fluorobenzoyl amido thiocarbamide and its preparation method and application | 广西中医药大学 | 2018-04-17 | — | — | CN | claimed |
| CN-106397420-A | 3-(5-aryl-1,3-4-oxadiazole-2-yl)sarisan derivatives, and preparation method and application thereof | 郑州大学 | 2017-02-15 | — | — | CN | claimed |
| CN-103483300-B | Preparation method of 5-cyanogen-1-(4-fluobenzene)-1,3-dihydrogenated-isobenzofuranone | UNIV SOUTHEAST | 2015-05-06 | — | — | CN | claimed |
| CN-104327043-A | Acridinethioether-typed derivative, preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2015-02-04 | — | — | CN | claimed |
| CN-102229576-B | Method for synthesizing 1,2,4-triazine compound by using micro-reactor | FUDAN UNIVERSITY (CN) | 2014-10-29 | — | — | CN | claimed |
| CN-103130766-B | Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide | UNIV NORTHWEST A&F | 2014-06-11 | — | — | CN | claimed |
| CN-103483300-A | Preparation method of 5-cyanogen-1-(4-fluobenzene)-1,3-dihydrogenated-isobenzofuranone | UNIV SOUTHEAST | 2014-01-01 | — | — | CN | claimed |
| CN-103130766-A | Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide | UNIV NORTHWEST A&F | 2013-06-05 | — | — | CN | claimed |
| CN-111107846-A | Heteroaryl allosteric modulators of nicotinic acetylcholine receptors | 默沙东公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-109705045-A | Pyrimidine anti-tumor compounds and its preparation method and application | 中国医科大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-106397420-B | 3- (5- aryl-1,3,4-oxdiazole -2- bases) asarinin analog derivative, preparation method and application | 郑州大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-108218848-A | A kind of trifluoromethyl pyridine oxadiazoles（Ether）Analog derivative and its application | 贵州大学 | 2018-06-29 | — | — | CN | disclosed |
| CN-105330651-B | 1 containing (miscellaneous) aryl and piperazine, 2,4- triazolinthione derivatives and preparation method and application | 南开大学 | 2018-05-01 | — | — | CN | disclosed |
| CN-1260239-C | Fructose spiro-compound with anti-cancer activity | UNIV BEIJING (CN) | 2006-06-21 | — | — | CN | disclosed |
| CN-1530371-A | Fructose spiro-compound with anti-cancer activity | 北京大学 | 2004-09-22 | — | — | CN | disclosed |
| CN-1148357-C | Triazole and imidazole derivative | - | 2004-05-05 | — | — | CN | disclosed |
| CN-1281852-A | Triazole and imidazole derivative | HOFFMANN LA ROCHE (CH) | 2001-01-31 | — | — | CN | disclosed |
| EP-0566446-A1 | Derivatives of indane-1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy | INNOTHERA (FR) | 1993-10-20 | — | — | EP | disclosed |
| WO-1993020046-A1 | INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR PREPARATION OF SAME AND THEIR USE AS THERAPEUTIC AGENTS | INNOTHERA (FR) | 1993-10-14 | — | — | WO | disclosed |