Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296575 | 0.88 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| SCHEMBL3884597 | 0.79 | TSHR (0.50) | ALDH1A1LMNAKDM4EL3MBTL1TSHR | |
| SCHEMBL3573439 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| SCHEMBL30597835 | 0.70 | TSHR (0.54) | ALDH1A1LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL30597839 | 0.68 | TSHR (0.56) | ALDH1A1LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL13815776 | 0.67 | RAB9A (0.55) | ALDH1A1LMNAKDM4ENPSR1TSHR | |
| SCHEMBL9591482 | 0.67 | KDM4E (0.46) | ALDH1A1LMNAKDM4EHPGDTDP1 | |
| SCHEMBL34468613 | 0.67 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EHPGDNPSR1 | |
| SCHEMBL26987310 | 0.66 | TSHR (0.48) | ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL2775305 | 0.66 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993017681-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |