Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30597835 | 0.85 | TSHR (0.54) | TSHRALDH1A1HSD17B10LMNARAB9A | |
| SCHEMBL26987310 | 0.84 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL30597839 | 0.82 | TSHR (0.56) | TSHRALDH1A1HSD17B10LMNARAB9A | |
| SCHEMBL15856620 | 0.82 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL13815776 | 0.81 | RAB9A (0.55) | TSHRALDH1A1HSD17B10LMNARAB9A | |
| SCHEMBL9544684 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1LMNACYP1A2KDM4E | |
| SCHEMBL31299641 | 0.79 | CYP2C9 (0.46) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3541912 | 0.78 | KDM4E (0.49) | TSHRALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL28353985 | 0.78 | LMNA (0.43) | TSHRALDH1A1HSD17B10LMNARAB9A | |
| SCHEMBL9638671 | 0.77 | LMNA (0.43) | TSHRALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | claimed |
| WO-2007086076-A2 | AN IMPROVED PROCESS FOR PREPARATION OF LEFLUNOMIDE | UNICHEM LABORATORIES LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| US-20030139606-A1 | Process for preparing 5-methylisoxazole-4-carboxylic- (4'-trifluoromethyl)-anilide | RAY ANUP KUMAR (US) | 2003-07-24 | — | — | US | claimed |
| WO-2003042193-A1 | PROCESS FOR PREPARING 5-METHYLISOXAZOLE-4-CARBOXYLIC-(4'-TRIFLUOROMETHYL)-ANILIDE | GENEVA PHARMACEUTICALS, INC. (US) | 2003-05-22 | — | — | WO | claimed |
| US-20260085048-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | EPIVARIO INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-12441689-B2 | ACSS2 inhibitors and methods of use thereof | EPIVARIO, INC. (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | disclosed |
| US-20230084752-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD. (IL) | 2023-03-16 | — | — | US | disclosed |
| EP-3969439-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2022-03-23 | — | — | EP | disclosed |
| CN-110669022-B | Micro-channel continuous preparation method of 5-methyl isoxazole-4-formic acid | 常州沃腾化工科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114127049-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-111233779-B | Preparation method of leflunomide | 廖文英 | 2021-08-20 | — | — | CN | disclosed |
| CN-1015256-B | PROCESS FOR PREPARING SUBSTITUTING COMPOUNDS OF BENZYL BUTENYL AMIDO | LILLY INDUSTRIES LTD (GB) | 1992-01-01 | — | — | CN | disclosed |
| EP-0257882-B1 | N-PHENYL BUTENAMIDES WITH PHARMACEUTICAL PROPERTIES | LILLY INDUSTRIES LIMITED (GB) | 1991-07-24 | — | — | EP | disclosed |
| US-4983619-A | Leukotriene antagonists | LILLY INDUSTRIES LIMITED (GB) | 1991-01-08 | — | — | US | disclosed |
| US-4892963-A | IMMUNE DISEASES | LILLY INDUSTRIES LIMITED (GB) | 1990-01-09 | — | — | US | disclosed |
| CN-87105515-A | Derivatives of phenylbutenamide compounds and preparation method thereof | — | 1988-03-23 | — | — | CN | disclosed |
| EP-0259972-A2 | Heterocyclic propene amide derivatives, processes for their preparation and their use as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1988-03-16 | — | — | EP | disclosed |
| EP-0257882-A1 | N-Phenyl butenamides with pharmaceutical properties | LILLY INDUSTRIES LIMITED (GB) | 1988-03-02 | — | — | EP | disclosed |
| CN-87105516-A | Phenyl crotonamide compound that replaces and preparation method thereof | — | 1988-02-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230084752-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | ACSS2, ADSS2, GLS2 | TSHR 3555/4885ALDH1A1 347/4885MEN1 658/4885 |
| US-20260085048-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | ACSS2, GLS2, ACSL3 | TSHR 1970/4885ALDH1A1 1031/4885MEN1 2249/4885 |
| US-12441689-B2 | ACSS2 inhibitors and methods of use thereof | ACSS2, ADSS2, GLS2 | TSHR 3555/4885ALDH1A1 347/4885MEN1 658/4885 |
| US-20030139606-A1 | Process for preparing 5-methylisoxazole-4-carboxylic- (4'-trifluoromethyl)-anilide | CA4, ACMSD, CA7 | TSHR 627/4885ALDH1A1 46/4885MEN1 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.