Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016629 | 0.81 | EGLN1 (0.43) | EGLN1NUDT1KDM4EDYRK1AADORA2A | |
| SCHEMBL3857164 | 0.79 | AKT2 (0.44) | AKT2NUDT1KDM4ECSNK2A1ADORA3 | |
| SCHEMBL11878666 | 0.79 | EGLN1 (0.40) | EGLN1NUDT1KDM4EDYRK1AADORA2A | |
| SCHEMBL30534246 | 0.78 | AKT2 (0.46) | AKT2NUDT1CSNK2A1ADORA3KIT | |
| SCHEMBL10910539 | 0.78 | ADORA2A (0.61) | EGLN1NUDT1KDM4EDYRK1ACSNK2A1 | |
| SCHEMBL1868817 | 0.78 | ADORA2A (0.43) | EGLN1NUDT1KDM4EDYRK1AADORA2A | |
| SCHEMBL5848453 | 0.77 | PI4KA (0.45) | EGLN1NUDT1KDM4EDYRK1AADORA3 | |
| SCHEMBL30109321 | 0.75 | NUDT1 (0.68) | AKT2NUDT1KDM4EADORA2AADORA1 | |
| SCHEMBL1059581 | 0.75 | NUDT1 (0.68) | AKT2NUDT1KDM4EADORA2AADORA1 | |
| SCHEMBL8906323 | 0.75 | AKT2 (0.44) | AKT2NUDT1CSNK2A1ADORA3KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036235-B1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-04-19 | — | — | EP | disclosed |
| EP-3036235-A1 | NEW BIS-AMIDO PYRIDINES | Boehringer Ingelheim International GmbH (DE) | 2016-06-29 | — | — | EP | disclosed |
| US-9249151-B2 | Bis-amido pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
| WO-2015025018-A1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-26 | — | — | WO | disclosed |
| US-20150057286-A1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| WO-1993018035-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057286-A1 | NEW BIS-AMIDO PYRIDINES | SMARCC1, MKI67, SMARCC2 | AKT2 2729/4885EGLN1 1248/4885NUDT1 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.