Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490464 | 0.80 | KDM4E (0.44) | ADORA2AADORA1PNPKDM4EMEN1 | |
| SCHEMBL42314 | 0.79 | ADORA2A (0.66) | ADORA2AADORA1ALDH1A1LMNATSHR | |
| SCHEMBL6016629 | 0.79 | EGLN1 (0.43) | ADORA2AADORA1EGLN1KDM4EMEN1 | |
| SCHEMBL29400753 | 0.79 | ADORA2A (0.66) | ADORA2AADORA1ALDH1A1LMNATSHR | |
| SCHEMBL9544742 | 0.78 | AKT2 (0.44) | ADORA2AADORA1EGLN1KDM4EMEN1 | |
| SCHEMBL11878666 | 0.77 | EGLN1 (0.40) | ADORA2AADORA1EGLN1KDM4EMEN1 | |
| SCHEMBL6829681 | 0.76 | ADORA2A (0.43) | ADORA2AADORA1PNPKDM4EMEN1 | |
| SCHEMBL320848 | 0.76 | NUDT1 (0.43) | ADORA2AADORA1PNPKDM4EMEN1 | |
| SCHEMBL6826187 | 0.76 | NUDT1 (0.44) | ADORA2AADORA1PNPKDM4EMEN1 | |
| SCHEMBL6831171 | 0.76 | ADORA2A (0.52) | ADORA2AADORA1PNPKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117795096-A | Methods, compositions and kits for preparing sequencing libraries | 吉复生物科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115884977-A | Stereoselective preparation of selected purine phosphoramidates | 阿堤亚制药公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-113292564-B | Synthetic method of 2-amino-6-chloropurine | 上海凌凯医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| WO-2019067740-A1 | FUSION PROTEINS HAVING A TOXIN AND CANCER MARKER, NANOPARTICLES, AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2019-04-04 | — | — | WO | disclosed |
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |
| EP-2847201-A2 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | The University of Queensland (AU) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013166545-A2 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2013-11-14 | — | — | WO | disclosed |
| EP-2494079-A1 | RAPID DETECTION OF MYCOPLASMA CONTAMINATION IN CELL CULTURE SAMPLES | Bio-Rad Laboratories, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011059802-A1 | RAPID DETECTION OF MYCOPLASMA CONTAMINATION IN CELL CULTURE SAMPLES | BIO-RAD LABORATORIES, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| EP-1534708-B1 | PURINE DERIVATIVES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS | CYCLACEL LTD (GB) | 2006-04-26 | — | — | EP | disclosed |
| EP-0773220-B1 | 2-Amino-6-chloropurine and method for preparing the same | SUMIKA FINE CHEMICALS CO LTD (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-6187921-B1 | 2-AMINO-6-CHLOROPURINE HAVING DOUBLE CONE-LIKE CRYSTAL FORM CONSTRUCTED BY COMBINING TWO PYRAMIDS WITH EACH OTHER AT THEIR BOTTOMS AND HAVING SPECIFIED AVERAGE PARTICLE DIAMETER | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-1017394-A1 | CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999002162-A1 | CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-01-21 | — | — | WO | disclosed |
| US-5789590-A | Double cone-like crystal form of 2-amino-6-chloropurine and preparation | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0773220-A1 | 2-Amino-6-chloropurine and method for preparing the same | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0719273-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007920-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1995-03-23 | — | — | WO | disclosed |
| US-5126347-A | Autoimmune deficiency syndrome | HOFFMANN-LA ROCHE INC. (US) | 1992-06-30 | — | — | US | disclosed |