Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 5/20 | 0.56 |
| ▸ | PRKCG | P05129 | 5/20 | 0.56 |
| ▸ | PRKCB | P05771 | 5/20 | 0.56 |
| ▸ | PRKCA | P17252 | 5/20 | 0.56 |
| ▸ | PRKCH | P24723 | 5/20 | 0.56 |
| ▸ | PRKCI | P41743 | 5/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.56 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.56 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.56 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | PRKACA | P17612 | 4/20 | 0.55 |
| ▸ | PRKACG | P22612 | 4/20 | 0.55 |
| ▸ | PRKACB | P22694 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542920 | 0.88 | PRKD3 (0.69) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9541958 | 0.85 | PRKD3 (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL2902584 | 0.78 | CYP3A4 (0.72) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9544838 | 0.76 | PRKCG (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL7434256 | 0.75 | PRKD3 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL23951500 | 0.74 | PRKD3 (0.71) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL2908265 | 0.74 | ROCK2 (0.67) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL7429827 | 0.73 | PRKD3 (0.60) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL21545920 | 0.73 | PRKD3 (0.69) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL7326397 | 0.73 | PRKD3 (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013072-A1 | 5-ISOQUINOLINESULFONAMIDE DERIVATIVES AS PROTEIN KINASE INHIBITING AGENTS | ITALFARMACO S.P.A. (IT) | 1993-07-08 | — | — | WO | disclosed |