Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.52 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544145 | 0.96 | CTSK (0.57) | CTSKHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9544253 | 0.88 | CTSK (0.47) | CTSKCTSBCTSLCTSSCAPN1 | |
| SCHEMBL9544528 | 0.85 | PPARA (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9544551 | 0.85 | PPARA (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9544644 | 0.85 | PPARA (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7304926 | 0.84 | CTSL (0.61) | CTSKCTSBCTSLCTSSCAPN1 | |
| SCHEMBL7304916 | 0.84 | CTSL (0.61) | CTSKCTSBCTSLCTSSCAPN1 | |
| SCHEMBL5191078 | 0.84 | CTSK (0.64) | CTSKCTSBCTSLCTSSCAPN1 | |
| SCHEMBL8823879 | 0.82 | CTSL (0.66) | CTSKCTSBCTSLCTSSCAPN1 | |
| SCHEMBL9544186 | 0.82 | HDAC3 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021211-A1 | AMIDES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATORIOS MENARINI S.A. (ES) | 1993-10-28 | — | — | WO | disclosed |