Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | TLR2 | O60603 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544832 | 0.88 | CTSK (0.55) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL9544817 | 0.87 | MEN1 (0.48) | TLR2CTSSCTSLMMEANPEP | |
| SCHEMBL9544145 | 0.84 | CTSK (0.57) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL11209394 | 0.83 | CTSK (0.58) | CTSKCTSSCTSLCTSBS1PR4 | |
| SCHEMBL27824395 | 0.83 | CTSK (0.58) | CTSKCTSSCTSLCTSBS1PR4 | |
| SCHEMBL9544814 | 0.82 | MEN1 (0.57) | TLR2MME | |
| SCHEMBL22475577 | 0.81 | LTA4H (0.57) | CTSKCTSBMMECAPN1 | |
| SCHEMBL20881521 | 0.81 | LTA4H (0.57) | CTSKCTSBMMECAPN1 | |
| SCHEMBL11680813 | 0.81 | LTA4H (0.57) | CTSKCTSBMMECAPN1 | |
| SCHEMBL7119787 | 0.81 | CTSK (0.56) | CTSKCTSSCTSLCTSBS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021211-A1 | AMIDES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATORIOS MENARINI S.A. (ES) | 1993-10-28 | — | — | WO | disclosed |