Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544782 | 0.89 | OPRD1 (0.36) | OPRD1PRMT5WDR77NR1D1 | |
| SCHEMBL9544069 | 0.89 | OPRD1 (0.36) | OPRD1PRMT5WDR77NR1D1 | |
| SCHEMBL9544151 | 0.87 | ACE (0.43) | RIPK1 | |
| SCHEMBL16681762 | 0.82 | ABCB1 (0.48) | ABCB1RIPK1 | |
| SCHEMBL16680417 | 0.82 | ABCB1 (0.48) | ABCB1RIPK1 | |
| SCHEMBL9544871 | 0.81 | HTRA1 (0.48) | OPRD1PRMT5WDR77NAMPTMEN1 | |
| SCHEMBL9543600 | 0.81 | HTRA1 (0.48) | OPRD1PRMT5WDR77NAMPTMEN1 | |
| SCHEMBL9542796 | 0.81 | OPRD1 (0.35) | OPRD1 | |
| SCHEMBL9542592 | 0.81 | BCL2 (0.33) | NR1D1 | |
| SCHEMBL9543404 | 0.81 | UCHL1 (0.53) | PRMT5WDR77RIPK1NAMPTUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |