Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543600 | 1.00 | HTRA1 (0.48) | HTRA1PRMT5WDR77OPRD1NAMPT | |
| SCHEMBL9542668 | 0.89 | HTRA1 (0.39) | HTRA1OPRD1NAMPT | |
| SCHEMBL9542442 | 0.89 | HTRA1 (0.39) | HTRA1OPRD1NAMPT | |
| SCHEMBL9545311 | 0.85 | PRMT5 (0.39) | PRMT5WDR77OPRD1NAMPTKMT2A | |
| SCHEMBL5064869 | 0.84 | OPRD1 (0.49) | PRMT5WDR77OPRD1NAMPTMEN1 | |
| SCHEMBL4595926 | 0.84 | OPRD1 (0.49) | PRMT5WDR77OPRD1NAMPTMEN1 | |
| SCHEMBL29163531 | 0.84 | OPRD1 (0.49) | PRMT5WDR77OPRD1NAMPTMEN1 | |
| SCHEMBL29401750 | 0.84 | OPRD1 (0.49) | PRMT5WDR77OPRD1NAMPTMEN1 | |
| SCHEMBL9544935 | 0.82 | HTRA1 (0.34) | HTRA1 | |
| SCHEMBL9544848 | 0.82 | UCHL1 (0.55) | OPRD1MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |