Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.32 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.32 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544871 | 0.82 | HTRA1 (0.48) | HTRA1 | |
| SCHEMBL9543600 | 0.82 | HTRA1 (0.48) | HTRA1 | |
| SCHEMBL9542442 | 0.76 | HTRA1 (0.39) | HTRA1 | |
| SCHEMBL9542668 | 0.76 | HTRA1 (0.39) | HTRA1 | |
| SCHEMBL9545311 | 0.69 | PRMT5 (0.39) | — | |
| SCHEMBL9544868 | 0.69 | OPRD1 (0.40) | NR1D1 | |
| SCHEMBL5064869 | 0.68 | OPRD1 (0.49) | NR1D1 | |
| SCHEMBL29401750 | 0.68 | OPRD1 (0.49) | NR1D1 | |
| SCHEMBL4595926 | 0.68 | OPRD1 (0.49) | NR1D1 | |
| SCHEMBL29163531 | 0.68 | OPRD1 (0.49) | NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |