Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NQO2 | P16083 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232686 | 0.87 | GAA (0.54) | GAASMN1; SMN2NOX1MAPTBRPF1 | |
| SCHEMBL4571024 | 0.85 | GAA (0.52) | GAASMN1; SMN2NOX1MAPTBRPF1 | |
| SCHEMBL27282680 | 0.85 | GAA (0.52) | GAASMN1; SMN2NOX1MAPTBRPF1 | |
| SCHEMBL4571018 | 0.85 | GAA (0.52) | GAASMN1; SMN2NOX1MAPTBRPF1 | |
| Adamantane SCHEMBL3892086 | 0.76 | BRPF1 (0.46) | GAASMN1; SMN2MAPTBRPF1KMT2A | |
| Sulfuric Acid SCHEMBL8008464 | 0.76 | GAA (0.53) | GAASMN1; SMN2MAPTBRPF1KMT2A | |
| SCHEMBL30938260 | 0.75 | NQO2 (0.52) | SMN1; SMN2MAPTKMT2ANQO2MAOA | |
| SCHEMBL29206064 | 0.75 | NQO2 (0.52) | SMN1; SMN2MAPTKMT2ANQO2MAOA | |
| SCHEMBL24457996 | 0.73 | ROS1 (0.46) | GAASMN1; SMN2NOX1MAPTBRPF1 | |
| SCHEMBL30136337 | 0.72 | KMT2A (0.51) | GAASMN1; SMN2NOX1MAPTBRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010266-A1 | DEVICE AND METHOD FOR DETECTION OF COMPOUNDS WHICH INTERCALATE WITH NUCLEIC ACIDS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1993-05-27 | — | — | WO | disclosed |