Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232686 | 0.97 | GAA (0.54) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| SCHEMBL4571018 | 0.95 | GAA (0.52) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| Adamantane SCHEMBL3892086 | 0.85 | BRPF1 (0.46) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| Phenazine SCHEMBL9545093 | 0.85 | GAA (0.48) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| Sulfuric Acid SCHEMBL8008464 | 0.85 | GAA (0.53) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| SCHEMBL24457996 | 0.82 | ROS1 (0.46) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| SCHEMBL15326896 | 0.81 | BRPF1 (0.42) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| SCHEMBL28919961 | 0.80 | GAA (0.41) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| SCHEMBL30136337 | 0.80 | KMT2A (0.51) | GAASMN1; SMN2BRPF1MAOAKMT2A | |
| SCHEMBL21952242 | 0.79 | BRPF1 (0.44) | GAASMN1; SMN2BRPF1MAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173803-B2 | Supramolecular scaffolds and methods of making the same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173803-B2 | Supramolecular scaffolds and methods of making the same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2012-05-08 | — | — | US | disclosed |
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041880-A1 | Supramolecular Scaffolds and Methods of Making the Same | BLM, TBXAS1, TOP2B | GAA 3447/4885SMN1; SMN2 2983/4885BRPF1 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.