Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134233 | 0.83 | TDP1 (0.56) | ALDH1A1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL9545436 | 0.77 | KMT2A (0.71) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7376588 | 0.77 | ALDH1A1 (0.89) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL265009 | 0.77 | RAB9A (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL8665732 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TP53MEN1KMT2ACRHBP | |
| SCHEMBL8174336 | 0.75 | NPC1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL28659194 | 0.74 | NPC1 (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL4929277 | 0.74 | MEN1 (0.77) | NPC1RAB9ASMN1; SMN2TAAR1MEN1 | |
| SCHEMBL11059936 | 0.74 | GAA (0.72) | ALDH1A1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL11487212 | 0.74 | CNR2 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993019040-A1 | PREPARATION OF OPTICALLY ACTIVE HYDRAZINES AND AMINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |