Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487212 | 0.89 | CNR2 (0.47) | TDP1L3MBTL1CNR2KMT2APOLB | |
| SCHEMBL9545549 | 0.88 | L3MBTL1 (0.51) | TDP1L3MBTL1KMT2APOLBALDH1A1 | |
| SCHEMBL9545436 | 0.86 | KMT2A (0.71) | TDP1L3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL9240012 | 0.83 | SMN1; SMN2 (0.62) | L3MBTL1KMT2APOLBALDH1A1TSHR | |
| SCHEMBL9545369 | 0.83 | ALDH1A1 (0.56) | L3MBTL1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL9110575 | 0.82 | KMT2A (0.50) | TDP1L3MBTL1CNR2KMT2AALDH1A1 | |
| SCHEMBL9516913 | 0.81 | L3MBTL1 (0.58) | TDP1L3MBTL1CNR2POLBALDH1A1 | |
| SCHEMBL9545457 | 0.81 | ALDH1A1 (0.52) | TDP1L3MBTL1KMT2AALDH1A1GLA | |
| SCHEMBL8652157 | 0.79 | ALDH1A1 (0.50) | TDP1L3MBTL1KMT2AALDH1A1GLA | |
| SCHEMBL4893297 | 0.78 | KDM4E (0.51) | TDP1KDM4EHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426223-A | Hydrogenation of n-acyl hydrazones in presence of catalyst comprising complex pf transition metal bonded to phosphine ligands | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-06-20 | — | — | US | disclosed |