Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706084 | 0.91 | LMNA (0.54) | TSHRALDH1A1LMNARARBTP53 | |
| SCHEMBL10593313 | 0.90 | RARB (0.64) | TSHRLMNARARBTP53KDM4E | |
| SCHEMBL8496546 | 0.87 | SLC6A3 (0.60) | TSHRLMNATP53CYP3A4TDP1 | |
| SCHEMBL5705937 | 0.87 | MAPT (0.54) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL8840791 | 0.87 | ALDH1A1 (0.68) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL2821623 | 0.87 | ALDH1A1 (0.68) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL8998305 | 0.87 | RARB (0.45) | TSHRALDH1A1LMNARARBTP53 | |
| SCHEMBL9163986 | 0.86 | PLK1 (0.62) | TSHRALDH1A1LMNARARBTP53 | |
| SCHEMBL7774426 | 0.86 | ALDH1A1 (0.63) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL7777056 | 0.86 | ALDH1A1 (0.63) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5186401-A | — | — | None | — | — | JP | disclosed |
| JP-H05186401-A | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | SHOWA SHELL SEKIYU KK | 1993-07-27 | — | — | JP | disclosed |