Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553089 | 0.90 | PTGS2 (0.67) | PTGS2KMT2AHSD17B10MEN1HPGD | |
| SCHEMBL12103324 | 0.89 | PTGS2 (0.57) | PTGS2KMT2AHSD17B10MEN1HPGD | |
| SCHEMBL27711379 | 0.88 | HCRTR1 (0.49) | PTGS2KMT2AHSD17B10MEN1HPGD | |
| SCHEMBL9082978 | 0.85 | PTGS2 (0.49) | PTGS2KMT2AHSD17B10MEN1HPGD | |
| SCHEMBL9085487 | 0.83 | MEN1 (0.55) | PTGS2KMT2AHSD17B10MEN1HPGD | |
| SCHEMBL4421848 | 0.83 | KMT2A (0.45) | PTGS2KMT2AHSD17B10MEN1HPGD | |
| SCHEMBL9082797 | 0.83 | MEN1 (0.50) | PTGS2KMT2AHSD17B10MEN1CYP2C9 | |
| SCHEMBL12986930 | 0.83 | PTGS2 (0.58) | PTGS2KMT2AHSD17B10MEN1HPGD | |
| SCHEMBL9083520 | 0.82 | TP53 (0.47) | PTGS2KMT2AHSD17B10MEN1HPGD | |
| SCHEMBL9084228 | 0.81 | MEN1 (0.57) | KMT2AHSD17B10MEN1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025542-A1 | BENZOXAZINONE AND BENZOTHIAZINONE DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO S.P.A. (IT) | 1993-12-23 | — | — | WO | disclosed |