Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699779 | 0.87 | LMNA (0.47) | KMT2ALMNAKDM4EHPGDPRKD3 | |
| SCHEMBL3004295 | 0.79 | LMNA (0.56) | KMT2ALMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL13208152 | 0.79 | LMNA (0.46) | KMT2ALMNASMN1; SMN2PRKD3PIM1 | |
| SCHEMBL9523341 | 0.77 | LMNA (0.43) | KMT2ALMNAKDM4EHPGDPRKD3 | |
| SCHEMBL9568344 | 0.75 | ALDH1A1 (0.43) | KMT2ALMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL9568297 | 0.75 | KDM4E (0.45) | KMT2ALMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL8320413 | 0.75 | LMNA (0.41) | KMT2ALMNAPRKD3PIM1GSK3A | |
| SCHEMBL12836206 | 0.74 | KMT2A (0.39) | KMT2ALMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL9568806 | 0.74 | LMNA (0.41) | KMT2ALMNAKDM4ESMN1; SMN2HPGD | |
| SCHEMBL9229273 | 0.74 | KMT2A (0.44) | KMT2ALMNAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025532-A1 | CARBOXYLIC ACID DERIVATIVE AND PRODUCTION THEREOF | NIPPON SHINYAKU CO., LTD. (JP) | 1993-12-23 | — | — | WO | disclosed |