Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3004295 | 0.89 | LMNA (0.56) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL1699779 | 0.83 | LMNA (0.47) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL12673659 | 0.81 | LMNA (0.55) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL4252158 | 0.80 | LMNA (0.52) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL9545795 | 0.79 | KMT2A (0.43) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL8320413 | 0.79 | LMNA (0.41) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL12673660 | 0.79 | LMNA (0.52) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL12665506 | 0.78 | LMNA (0.51) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL9568381 | 0.76 | LMNA (0.49) | LMNAPIM1GSK3AGSK3BPIM3 | |
| SCHEMBL12665505 | 0.76 | LMNA (0.49) | LMNAPIM1GSK3AGSK3BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197910-A1 | PROCESS FOR PREPARATION OF PRULIFLOXACIN USING NOVEL INTERMEDIATES | HETERO DRUGS LIMITED (IN) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197910-A1 | PROCESS FOR PREPARATION OF PRULIFLOXACIN USING NOVEL INTERMEDIATES | KCNH1, QDPR, DPYD | LMNA 3268/4885PIM1 2736/4885GSK3A 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.