Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 1.00 |
| ▸ | GRB2 | P62993 | 1/20 | 0.66 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | XIAP | P98170 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.55 |
| ▸ | PGK1 | P00558 | 2/20 | 0.55 |
| ▸ | PGK2 | P07205 | 2/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonodifluoromethyl Phenylalanine SCHEMBL2517439 | 1.00 | PTPN1 (1.00) | PTPN1GRB2SLC7A5ALPIPKM | |
| Phosphonodifluoromethyl Phenylalanine SCHEMBL2517440 | 1.00 | PTPN1 (1.00) | PTPN1GRB2SLC7A5ALPIPKM | |
| SCHEMBL27715838 | 0.88 | PTPN1 (0.78) | PTPN1GRB2PTPN2PTPN6PTPN11 | |
| SCHEMBL13997109 | 0.87 | PTPN1 (0.76) | PTPN1GRB2SLC7A5ALPIPKM | |
| SCHEMBL7831965 | 0.86 | PTPN1 (0.75) | PTPN1PTPN2PTPN6PTPN11PGK1 | |
| SCHEMBL43861 | 0.82 | GRB2 (0.76) | PTPN1GRB2SLC7A5ALPIPKM | |
| SCHEMBL148122 | 0.82 | GRB2 (0.76) | PTPN1GRB2SLC7A5ALPIPKM | |
| SCHEMBL43862 | 0.82 | GRB2 (0.76) | PTPN1GRB2SLC7A5ALPIPKM | |
| Dl-Phenylalanine SCHEMBL28313877 | 0.81 | SLC7A5 (0.71) | PTPN1GRB2SLC7A5ALPIPKM | |
| SCHEMBL2423462 | 0.81 | PTPN1 (0.67) | PTPN1GRB2SLC7A5ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025561-A1 | PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-12-23 | — | — | WO | claimed |