Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.69 |
| ▸ | CTSB | P07858 | 3/20 | 0.69 |
| ▸ | CTSS | P25774 | 1/20 | 0.69 |
| ▸ | CTSK | P43235 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TACR1 | P25103 | 2/20 | 0.67 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329686 | 0.94 | ALDH1A1 (0.74) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL7151822 | 0.94 | ALDH1A1 (0.74) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL8106977 | 0.94 | ALDH1A1 (0.63) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL8053250 | 0.94 | CTSL (0.65) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL13287085 | 0.94 | ALDH1A1 (0.63) | CTSLCTSBCTSSCTSKALDH1A1 | |
| Hydrochloric Acid SCHEMBL7928050 | 0.93 | ALDH1A1 (0.72) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL240653 | 0.92 | ALDH1A1 (0.62) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL27395816 | 0.92 | ALDH1A1 (0.62) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL9301372 | 0.92 | ALDH1A1 (0.62) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL9402445 | 0.92 | ALDH1A1 (0.62) | CTSLCTSBCTSSCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272564-B1 | Enzyme mediated coupling reactions | HAMPSHIRE CHEMICAL CORP (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5002872-A | Peptides, Liquid Phase, Acetonitrile, Water | W. R. GRACE & CO.-CONN. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0272564-A2 | Enzyme mediated coupling reactions | HAMPSHIRE CHEMICAL CORPORATION (US) | 1988-06-29 | — | — | EP | disclosed |