Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696623 | 0.86 | HTT (0.32) | HTT | |
| SCHEMBL9546008 | 0.83 | HTT (0.45) | HTT | |
| SCHEMBL9578357 | 0.82 | POLB (0.38) | ALDH1A1LMNAMAPK1TSHRPOLB | |
| SCHEMBL2367717 | 0.81 | LMNA (0.39) | ALDH1A1LMNAMAPK1TSHRPOLB | |
| SCHEMBL2367713 | 0.81 | TSHR (0.43) | ALDH1A1LMNAMAPK1TSHRPOLB | |
| SCHEMBL9545989 | 0.80 | TSHR (0.35) | LMNATSHRHTTNPSR1TDP1 | |
| SCHEMBL2526807 | 0.79 | TSHR (0.37) | ALDH1A1LMNAMAPK1TSHRPOLB | |
| SCHEMBL227643 | 0.78 | TSHR (0.47) | ALDH1A1LMNAMAPK1TSHRPOLB | |
| SCHEMBL5667653 | 0.78 | TSHR (0.36) | ALDH1A1LMNAMAPK1TSHRPOLB | |
| SCHEMBL7169915 | 0.78 | TSHR (0.39) | ALDH1A1LMNAMAPK1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |
| US-5235013-A | Copolymerizing an alkene of 6-10 carbons having one double bond and a side chain methyl group and an acrylic or fluoroacrylic ester | CIBA-GEIGY CORPORATION | 1993-08-10 | — | — | US | disclosed |
| EP-0478261-A2 | Process for producing oxygen-permeable polymer | CIBA-GEIGY AG (CH) | 1992-04-01 | — | — | EP | disclosed |