Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.30 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.30 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954608 | 0.91 | CRBN (0.46) | CRBNPKMDUTDDB1 | |
| SCHEMBL4347792 | 0.81 | CRBN (0.47) | CRBNPKMDUTDDB1ALDH1A1 | |
| SCHEMBL16671886 | 0.80 | GPR84 (0.43) | CRBNPKM | |
| Thiourea SCHEMBL27613159 | 0.80 | CRBN (0.44) | CRBNPKMDUTDDB1ALDH1A1 | |
| SCHEMBL8653846 | 0.79 | GPR84 (0.46) | CRBNPKM | |
| SCHEMBL8656959 | 0.77 | CRBN (0.48) | CRBNPKMDUTDDB1ALDH1A1 | |
| Methimazole SCHEMBL8813156 | 0.75 | CRBN (0.39) | CRBNPKMDUT | |
| SCHEMBL27578551 | 0.74 | CRBN (0.46) | CRBNPKMDUTDDB1ALDH1A1 | |
| SCHEMBL5613633 | 0.69 | ALDH1A1 (0.40) | CRBNPKMDUTALDH1A1LMNA | |
| SCHEMBL28747347 | 0.69 | DUT (0.38) | CRBNPKMDUTDDB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117363716-A | Detection reagent and kit for mutation sites of genes related to drug-induced granulocytopenia and liver injury and application of detection reagent and kit | 济南爱新卓尔医学检验有限公司 | 2024-01-09 | — | — | CN | disclosed |