Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 6/20 | 0.35 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546247 | 1.00 | TRPA1 (0.36) | TRPA1NR4A2PTGIRPRKCAABHD16A | |
| SCHEMBL9546352 | 0.91 | NR4A2 (0.45) | TRPA1NR4A2PTGIRPPARGGPR132 | |
| SCHEMBL9546348 | 0.91 | NR4A2 (0.45) | TRPA1NR4A2PTGIRPPARGGPR132 | |
| SCHEMBL9546333 | 0.85 | PRKCA (0.31) | PRKCA | |
| SCHEMBL9546316 | 0.84 | NR4A2 (0.36) | TRPA1NR4A2PTGIRPRKCAABHD16A | |
| SCHEMBL9546322 | 0.84 | NR4A2 (0.36) | TRPA1NR4A2PTGIRPRKCAABHD16A | |
| SCHEMBL9546196 | 0.83 | PRKCA (0.36) | TRPA1NR4A2PTGIRPRKCAABHD16A | |
| SCHEMBL9546194 | 0.83 | PRKCA (0.36) | TRPA1NR4A2PTGIRPRKCAABHD16A | |
| SCHEMBL10514313 | 0.81 | PTGER4 (0.35) | TRPA1NR4A2PTGIR | |
| SCHEMBL9546263 | 0.79 | PTGER3 (0.43) | TRPA1NR4A2PTGIRABHD16APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |