Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | PTGIR | P43119 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546316 | 1.00 | NR4A2 (0.36) | NR4A2TRPA1PTGIRTSHRPTGER4 | |
| SCHEMBL9546247 | 0.84 | TRPA1 (0.36) | NR4A2TRPA1PTGIRPRKCAABHD16A | |
| SCHEMBL9546243 | 0.84 | TRPA1 (0.36) | NR4A2TRPA1PTGIRPRKCAABHD16A | |
| SCHEMBL9546194 | 0.83 | PRKCA (0.36) | NR4A2TRPA1PTGIRTSHRPTGER4 | |
| SCHEMBL9546196 | 0.83 | PRKCA (0.36) | NR4A2TRPA1PTGIRTSHRPTGER4 | |
| SCHEMBL9546081 | 0.80 | PTGER3 (0.43) | NR4A2TRPA1PTGER4PTGER2ALDH1A1 | |
| SCHEMBL9546084 | 0.80 | PTGER3 (0.43) | NR4A2TRPA1PTGER4PTGER2ALDH1A1 | |
| SCHEMBL9546352 | 0.74 | NR4A2 (0.45) | NR4A2TRPA1PTGIRTSHRPTGER4 | |
| SCHEMBL9546348 | 0.74 | NR4A2 (0.45) | NR4A2TRPA1PTGIRTSHRPTGER4 | |
| SCHEMBL10603408 | 0.73 | NR4A2 (0.50) | NR4A2TRPA1PTGIRTSHRPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |