Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546351 | 1.00 | ALDH1A1 (0.35) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9546251 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9546246 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL10606628 | 0.78 | MAPT (0.37) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL10606636 | 0.78 | MAPT (0.37) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9546340 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9546343 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL10620015 | 0.70 | NFKB1 (0.53) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL10620026 | 0.70 | NFKB1 (0.53) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9546137 | 0.69 | L3MBTL1 (0.31) | ALDH1A1KMT2AMAPTMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |