SCHEMBL9546404

SCHEMBL9546404

C=C(c1ccc(CN=C=O)cc1)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.33
HDAC1 Q13547 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
MIF P14174 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157638 0.81 MEP1B (0.34) MIF
SCHEMBL6568210 0.81 TRPA1 (0.36) TRPA1MIF
SCHEMBL23686810 0.77 TDP1 (0.37)
SCHEMBL5697429 0.76 TRPA1 (0.35) TRPA1MIF
SCHEMBL21089 0.75 MIF (0.44) TRPA1MIF
SCHEMBL4667307 0.74 CYP3A4 (0.42) TRPA1
Water SCHEMBL14972874 0.73 MIF (0.43) TRPA1MIF
SCHEMBL22471901 0.73 MIF (0.43) TRPA1MIF
Water SCHEMBL29040332 0.73 MIF (0.43) TRPA1MIF
SCHEMBL23686861 0.73 MAPT (0.38) HDAC1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0351534-B1 POLYFUNCTIONAL MONOMERS AND PROCESS FOR PRODUCTION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP claimed
EP-0351534-A2 Polyfunctional monomers and process for production thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-24 EP claimed
US-9523009-B2 Alcohol-based printing ink composition TOYO INK SC HOLDINGS CO., LTD. (JP) 2016-12-20 US disclosed
US-20130289185-A1 ALCOHOL-BASED PRINTING INK COMPOSITION TOYO INK CO., LTD. (JP) 2013-10-31 US disclosed