Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807677 | 0.81 | CYP3A4 (0.39) | CYP3A4TSHRTRPA1MAPK1TDP1 | |
| SCHEMBL4935768 | 0.79 | CYP3A4 (0.47) | CYP3A4TSHRTRPA1MAPK1TDP1 | |
| SCHEMBL330724 | 0.78 | CYP3A4 (0.50) | CYP3A4TSHRTRPA1MAPK1TDP1 | |
| SCHEMBL8461563 | 0.77 | MAPT (0.35) | — | |
| SCHEMBL13811504 | 0.75 | CYP3A4 (0.52) | CYP3A4TSHRTRPA1MAPK1TDP1 | |
| SCHEMBL11796884 | 0.74 | CYP3A4 (0.50) | CYP3A4TSHRTRPA1MAPK1TDP1 | |
| SCHEMBL9546404 | 0.74 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL10488686 | 0.73 | CYP3A4 (0.54) | CYP3A4TSHRTRPA1MAPK1TDP1 | |
| SCHEMBL219763 | 0.72 | NOS3 (0.55) | CYP3A4TSHRTRPA1MAPK1TDP1 | |
| SCHEMBL15430 | 0.72 | CYP3A4 (0.70) | CYP3A4TSHRTRPA1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1941518-A1 | METHOD FOR ELECTRICAL INSULATION VIA APPLYING A POLY (ARYLENE ETHER) COMPOSITION AND INSULATED ELECTRICAL CONDUCTOR | General Electric Company (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007037940-A1 | METHOD FOR ELECTRICAL INSULATION VIA APPLYING A POLY (ARYLENE ETHER) COMPOSITION AND INSULATED ELECTRICAL CONDUCTOR | GENERAL ELECTRIC COMPANY (US) | 2007-04-05 | — | — | WO | disclosed |