Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546461 | 0.80 | TRPA1 (0.36) | PPARGPPARA | |
| SCHEMBL9546109 | 0.77 | PPARG (0.30) | PPARG | |
| SCHEMBL9546383 | 0.76 | PPARG (0.31) | PPARGPPARA | |
| SCHEMBL9546206 | 0.75 | PPARG (0.38) | PPARGPTGER3PTGER4PPARA | |
| SCHEMBL9546204 | 0.74 | PPARG (0.36) | PPARGPTGER3PTGER4PPARA | |
| SCHEMBL10620216 | 0.69 | PTGIR (0.33) | PPARGPPARA | |
| SCHEMBL9546174 | 0.67 | — | — | |
| SCHEMBL8909641 | 0.66 | LTB4R (0.46) | — | |
| SCHEMBL11118818 | 0.65 | TRPA1 (0.36) | — | |
| SCHEMBL7614865 | 0.65 | TSHR (0.54) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216183-A | Antitumor, anticarcinogenic agents; bone formation accelerators | TEIJIN LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |