Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546383 | 0.92 | PPARG (0.31) | PPARG | |
| SCHEMBL9546461 | 0.83 | TRPA1 (0.36) | PPARG | |
| SCHEMBL9546110 | 0.80 | — | — | |
| SCHEMBL9546318 | 0.79 | TRPA1 (0.43) | PPARG | |
| SCHEMBL9546323 | 0.79 | TRPA1 (0.43) | PPARG | |
| SCHEMBL9546211 | 0.77 | PPARG (0.35) | PPARG | |
| SCHEMBL9546097 | 0.75 | PTGER2 (0.34) | PPARG | |
| SCHEMBL9546100 | 0.75 | TRPA1 (0.34) | PPARG | |
| SCHEMBL9546174 | 0.74 | — | — | |
| SCHEMBL10619335 | 0.73 | PPARG (0.30) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216183-A | Antitumor, anticarcinogenic agents; bone formation accelerators | TEIJIN LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |