Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SOD1 | P00441 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808062 | 0.78 | TEAD1 (0.53) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL10981879 | 0.78 | KMT2A (0.50) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL907105 | 0.76 | KMT2A (0.48) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL14303351 | 0.76 | MAOA (0.44) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL1705451 | 0.74 | KMT2A (0.47) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL9808069 | 0.74 | KDM4E (0.55) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL2729285 | 0.74 | NPC1 (0.45) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL9808024 | 0.74 | KDM4E (0.59) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL14666345 | 0.74 | KMT2A (0.47) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL14821022 | 0.74 | SMN1; SMN2 (0.48) | KMT2AMEN1RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023370-A1 | PROCESS FOR THE PREPARATION OF FLUOROMETHYL THIO BENZENES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5243080-A | Ether and ester compounds | ALLIEDSIGNAL INC. (US) | 1993-09-07 | — | — | US | disclosed |
| US-5162587-A | METHOD FOR FLUORINATING BY USING N-FLUOROPYRIDINIUM PYRIDINE HEPTAFLUORODIBORATE | ALLIED-SIGNAL INC. | 1992-11-10 | — | — | US | disclosed |
| WO-1992012983-A1 | A METHOD OF FLUORINATING BY USING N-FLUOROPYRIDINIUM PYRIDINE HEPTAFLUORODIBORATE | ALLIED-SIGNAL INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| US-5086190-A | Heating and reacting androstadienes with the complexes in solvent | ALLIED-SIGNAL INC. (US) | 1992-02-04 | — | — | US | disclosed |