Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022447 | 0.81 | TSHR (0.39) | GAADDB1CRBNHTTTSHR | |
| SCHEMBL1322979 | 0.80 | RAB9A (0.49) | GAARAB9AHTTKDM4EALDH1A1 | |
| Benzene SCHEMBL27893007 | 0.77 | TSHR (0.43) | GAADDB1CRBNRAB9AHTT | |
| SCHEMBL10603303 | 0.75 | NPC1 (0.48) | CRBNKDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL27296485 | 0.74 | MAP3K14 (0.33) | GAADDB1CRBNRAB9AKDM4E | |
| SCHEMBL6328278 | 0.73 | ALDH1A1 (0.36) | GAATP53TSHRKDM4EALDH1A1 | |
| SCHEMBL6619679 | 0.72 | RAB9A (0.37) | GAARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL29967266 | 0.71 | MAPK1 (0.42) | GAADDB1CRBNALDH1A1MAPK1 | |
| SCHEMBL5227458 | 0.70 | GPBAR1 (0.51) | GAADDB1CRBNRAB9ATSHR | |
| SCHEMBL274968 | 0.70 | GPBAR1 (0.51) | GAADDB1CRBNRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |