Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12569402 | 0.89 | ALDH1A1 (0.53) | ALDH1A1HTR2AHRH1TAAR1MAOA | |
| SCHEMBL11566485 | 0.84 | MAOA (0.55) | HTR2AHRH1TAAR1MAOACYP2A6 | |
| SCHEMBL7896300 | 0.84 | CTSK (0.49) | TAAR1MAOASLC6A2CYP2A6SLC6A4 | |
| SCHEMBL28232854 | 0.82 | TAAR1 (0.38) | ALDH1A1TAAR1MAOASLC6A2CYP2A6 | |
| SCHEMBL11565732 | 0.81 | MAOA (0.56) | HTR2ATAAR1MAOACYP2A6SMN1; SMN2 | |
| SCHEMBL11568144 | 0.81 | MAOA (0.56) | HTR2ATAAR1MAOACYP2A6SMN1; SMN2 | |
| SCHEMBL2554330 | 0.81 | TAAR1 (0.48) | ALDH1A1TAAR1MAOASLC6A2CYP2A6 | |
| SCHEMBL9546973 | 0.81 | TAAR1 (0.48) | ALDH1A1TAAR1MAOASLC6A2CYP2A6 | |
| SCHEMBL791591 | 0.80 | TAAR1 (0.50) | TAAR1MAOASLC6A2CYP2A6SLC6A4 | |
| SCHEMBL14402897 | 0.79 | CTSK (0.46) | TAAR1MAOASLC6A2CYP2A6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002721-A2 | Process for preparing hydrazines | BAYER AG (DE) | 1979-07-11 | — | — | EP | disclosed |