Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176236 | 0.86 | TSHR (0.39) | ALDH1A1SMN1; SMN2TSHRCA12CA1 | |
| SCHEMBL9547084 | 0.81 | DPP4 (0.38) | ZDHHC20ZDHHC2TSHRDPP4CYP1A2 | |
| SCHEMBL7524699 | 0.77 | DPP4 (0.50) | ZDHHC20ZDHHC2ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9547277 | 0.76 | ZDHHC20 (0.38) | ZDHHC20ZDHHC2DPP4CYP3A4MAPT | |
| SCHEMBL3170799 | 0.75 | TSHR (0.40) | TSHRTDP1 | |
| SCHEMBL3170526 | 0.73 | TSHR (0.44) | ZDHHC20ZDHHC2ALDH1A1TSHRNPSR1 | |
| SCHEMBL7524652 | 0.73 | ALDH1A1 (0.40) | ZDHHC20ZDHHC2ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9547288 | 0.72 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2DPP4MAPT | |
| SCHEMBL3160765 | 0.72 | TSHR (0.36) | ALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL3177444 | 0.71 | TSHR (0.37) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |