Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329686 | 0.79 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1NPSR1MAPT | |
| Hydrochloric Acid SCHEMBL9547190 | 0.78 | ACHE (0.37) | TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20793437 | 0.77 | MEN1 (0.38) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1069147 | 0.76 | — | — | |
| SCHEMBL8868580 | 0.76 | MEN1 (0.36) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9382302 | 0.76 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10458335 | 0.75 | ALDH1A1 (0.47) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL19555331 | 0.75 | ACHE (0.51) | ALDH1A1 | |
| SCHEMBL6993745 | 0.74 | MAPT (0.43) | TSHRSMN1; SMN2ALDH1A1NPSR1MEN1 | |
| SCHEMBL4680857 | 0.74 | CASP1 (0.45) | MEN1KMT2AMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |