Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.63 |
| ▸ | F2 | P00734 | 3/20 | 0.63 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.63 |
| ▸ | PLAU | P00749 | 2/20 | 0.63 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.63 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.63 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.63 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.63 |
| ▸ | PLG | P00747 | 1/20 | 0.63 |
| ▸ | S100B | P04271 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.63 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | AOC1 | P19801 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547428 | 0.93 | LTB4R (0.60) | PRSS1PRMT1F2ST14PLAU | |
| SCHEMBL9547436 | 0.88 | PRSS1 (0.63) | PRSS1PRMT1F2ST14PLAU | |
| SCHEMBL9547445 | 0.83 | PRMT1 (0.71) | PRSS1PRMT1F2ST14PLAU | |
| SCHEMBL9547437 | 0.82 | LTB4R (0.59) | PRSS1PRMT1F2ST14PLAU | |
| SCHEMBL9547441 | 0.81 | LTB4R (0.63) | PRSS1PRMT1F2ST14PLAU | |
| Hydrochloric Acid SCHEMBL9547451 | 0.81 | PRSS1 (0.70) | PRSS1PRMT1F2ST14PLAU | |
| SCHEMBL9547462 | 0.81 | ALDH1A1 (0.52) | PRSS1PRMT1F2ST14PLAU | |
| SCHEMBL12989557 | 0.80 | F2 (0.76) | PRSS1PRMT1F2ST14PLAU | |
| SCHEMBL14599639 | 0.80 | PRMT1 (1.00) | PRSS1PRMT1F2ST14PLAU | |
| Pentamidine SCHEMBL3329 | 0.80 | PRMT1 (1.00) | PRSS1PRMT1F2ST14PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246965-A | Leukotriene antagonist | CIBA-GEIGY (US) | 1993-09-21 | — | — | US | claimed |
| EP-0518818-A2 | Arylethers, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | claimed |
| EP-0518818-A2 | Arylethers, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | disclosed |