Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416802 | 0.87 | MAPT (0.41) | EPHX1MAPTNPSR1EPHX2 | |
| SCHEMBL9416729 | 0.77 | MAPT (0.38) | EPHX1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL4825718 | 0.72 | NPSR1 (0.42) | DGAT1BTKMAPTNPSR1MEN1 | |
| SCHEMBL16987661 | 0.71 | DGAT1 (0.40) | DGAT1NPSR1MEN1MAPK1KMT2A | |
| SCHEMBL30288761 | 0.70 | CHRM2 (0.37) | DGAT1BTKMAPTNPSR1CHRM2 | |
| SCHEMBL25642139 | 0.70 | CHRM2 (0.37) | DGAT1BTKMAPTNPSR1CHRM2 | |
| SCHEMBL31547413 | 0.69 | LMNA (0.38) | MAPTNPSR1MEN1KMT2A | |
| SCHEMBL31547416 | 0.69 | LMNA (0.38) | MAPTNPSR1MEN1KMT2A | |
| SCHEMBL5435228 | 0.67 | MAPK1 (0.41) | CHRM2CHRM1CHRM3MEN1MAPK1 | |
| SCHEMBL21679086 | 0.67 | DGAT1 (0.40) | DGAT1NPSR1MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278914-B1 | PROCESS FOR THE PREPARATION OF TERT.-ALKYL ESTERS OF SUCCINIC ACID | CIBA-GEIGY AG (CH) | 1993-09-22 | — | — | EP | disclosed |
| US-4904814-A | CATALYTIC TRANSESTERIFICATION OF METHYL OR ETHYL ESTERS WITH TERTIARY ALCOHOL | CIBA-GEIGY CORPORATION (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0278914-A2 | Process for the preparation of tert.-alkyl esters of succinic acid | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | disclosed |