Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416802 | 0.89 | MAPT (0.41) | MAPTNPSR1EPHX1SMN1; SMN2NPC1 | |
| SCHEMBL9547514 | 0.77 | GAA (0.36) | MAPTNPSR1EPHX1MEN1KMT2A | |
| SCHEMBL22640750 | 0.77 | CES2 (0.39) | MAPTEPHX1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30706764 | 0.73 | HTT (0.32) | MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL31547413 | 0.71 | LMNA (0.38) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28786480 | 0.71 | HSD11B1 (0.37) | EPHX1 | |
| SCHEMBL31547416 | 0.71 | LMNA (0.38) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28786461 | 0.71 | HSD11B1 (0.37) | EPHX1 | |
| SCHEMBL3118786 | 0.67 | MAPT (0.38) | MAPTNPSR1EPHX1CYP4F2CYP4A11 | |
| SCHEMBL14260950 | 0.67 | MAPT (0.41) | MAPTNPSR1EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292937-A | Use of malonic acid derivative compounds for retarding plant growth | RHONE-POULENC INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |