Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | BID | P55957 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547631 | 0.98 | PPARA (0.41) | CYP1A2PPARARARBALDH1A1ALOX15 | |
| SCHEMBL9547567 | 0.98 | PPARA (0.41) | CYP1A2PPARARARBALDH1A1ALOX15 | |
| SCHEMBL9547628 | 0.96 | CYP1A2 (0.42) | CYP1A2PPARARARBALDH1A1ALOX15 | |
| SCHEMBL106659 | 0.91 | CYP1A2 (0.46) | CYP1A2ALDH1A1ALOX15SELLSELP | |
| SCHEMBL5072778 | 0.89 | PPARA (0.54) | PPARARARBALDH1A1PPARGBID | |
| SCHEMBL11146346 | 0.89 | PPARA (0.54) | PPARARARBALDH1A1PPARGBID | |
| SCHEMBL19953532 | 0.89 | PPARA (0.54) | PPARARARBALDH1A1PPARGBID | |
| SCHEMBL1264820 | 0.89 | PPARA (0.54) | PPARARARBALDH1A1PPARGBID | |
| SCHEMBL5072798 | 0.88 | GABRP (0.49) | CYP1A2PPARARARBALDH1A1ALOX15 | |
| SCHEMBL31153153 | 0.87 | PPARA (0.37) | CYP1A2PPARARARBALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5115089-A | Heat resistant polymers for electrical insulation, protective coatings for electronics formed by reaction of tetracarboxylic dianhydrides and diaminoamides and diamines | HITACHI CHEMICAL CO., LTD. (JP) | 1992-05-19 | — | — | US | claimed |
| US-20120202015-A1 | METHOD FOR MANUFACTURING ADHESION BODY, METHOD FOR MANUFACTURING SUBSTRATE WITH ADHESIVE PATTERN, AND SUBSTRATE WITH ADHESIVE PATTERN | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2012-08-09 | — | — | US | disclosed |
| EP-0308270-B1 | Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof | HITACHI CHEMICAL CO LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5115089-A | Heat resistant polymers for electrical insulation, protective coatings for electronics formed by reaction of tetracarboxylic dianhydrides and diaminoamides and diamines | HITACHI CHEMICAL CO., LTD. (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0308270-A2 | Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof | Hitachi Chemical Co., Ltd. (JP) | 1989-03-22 | — | — | EP | disclosed |