SCHEMBL9547732

SCHEMBL9547732

FC(F)(F)c1[c]c(C(F)(F)F)c2c(c1)CCC2

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
GPR35 Q9HC97 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9779444 0.66
SCHEMBL9565276 0.63
SCHEMBL9779703 0.62 MAOA (0.36) MEN1KMT2A
SCHEMBL15532189 0.62 MEN1 (0.35) MEN1USP2HTTKMT2AKEAP1
SCHEMBL21033060 0.60 MEN1 (0.35) MEN1USP2HTTKMT2AKEAP1
SCHEMBL9160577 0.60 MAPT (0.31)
SCHEMBL3644366 0.60
SCHEMBL20400001 0.59 MAPT (0.35) MEN1KMT2A
SCHEMBL22861176 0.58 MEN1 (0.33) MEN1USP2HTTKMT2AKEAP1
SCHEMBL19679242 0.57 BCL2L1 (0.42) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0256981-B1 TITANOCENES AND THEIR USE CIBA-GEIGY AG (CH) 1993-02-17 EP disclosed
US-4963470-A PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1990-10-16 US disclosed
US-4855468-A Titanocenes and a radiation-polymerizable composition containing these titanocenes CIBA-GEIGY CORPORATION (US) 1989-08-08 US disclosed
EP-0186626-B1 TITANOCENES AND COMPOSITIONS CURABLE BY IRRADIATION CONTAINING THESE TITANOCENES CIBA-GEIGY AG (CH) 1988-09-14 EP disclosed
EP-0256981-A2 Titanocenes and their use CIBA-GEIGY AG (CH) 1988-02-24 EP disclosed
US-4713401-A PHOTOINITIATORS ORTHO-CF2Z GROUP CIBA SPECIALTY CHEMICALS CORPORATION 1987-12-15 US disclosed
EP-0186626-A2 Titanocenes and compositions curable by irradiation containing these titanocenes CIBA-GEIGY AG (CH) 1986-07-02 EP disclosed