SCHEMBL9779703

SCHEMBL9779703

FC(F)(F)c1[c]c(C(F)(F)F)c2c(c1)Cc1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.36
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
KDM4E B2RXH2 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 3/20 0.32
HSD17B10 Q99714 3/20 0.32
TSHR P16473 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547857 0.70 SMN1; SMN2 (0.44) MAOAMAPTSMN1; SMN2KDM4ENPC1
SCHEMBL9155890 0.68 MAOA (0.39) MAOAMAPTSMN1; SMN2KDM4ENPC1
SCHEMBL2963744 0.67 AR (0.34) MAOAMAPTSMN1; SMN2KDM4ENPC1
SCHEMBL2962089 0.65 KDM4E (0.38) MAOAMAPTSMN1; SMN2KDM4ENPC1
SCHEMBL30403300 0.64 MAOA (0.56) MAOAMAPTSMN1; SMN2KDM4ENPC1
SCHEMBL5929222 0.63 ALDH1A1 (0.35) MAPTKDM4EALDH1A1HPGDCYP3A4
Fluorene SCHEMBL8180 0.62 MAOA (0.68) MAOAMAPTSMN1; SMN2KDM4ENPC1
Fluorene SCHEMBL31388525 0.62 MAOA (0.68) MAOAMAPTSMN1; SMN2KDM4ENPC1
Fluorene SCHEMBL29355380 0.62 MAOA (0.68) MAOAMAPTSMN1; SMN2KDM4ENPC1
Fluorene SCHEMBL29478468 0.62 MAOA (0.68) MAOAMAPTSMN1; SMN2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277915-B1 PHOTOINITIATOR MIXTURE CONTAINING A TITANOCENE AND A 3-KETOCOUMARIN CIBA-GEIGY AG (CH) 1991-09-04 EP disclosed
US-5011755-A Relief Images CIBA-GEIGY CORPORATION (US) 1991-04-30 US disclosed
EP-0277915-A2 Photoinitiator mixture containing a titanocene and a 3-ketocoumarin CIBA-GEIGY AG (CH) 1988-08-10 EP disclosed