Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.51 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940823 | 0.80 | KMT2A (0.62) | CES2CES1L3MBTL1FFAR1TDP1 | |
| SCHEMBL1681600 | 0.80 | PLAAT3 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4L3MBTL1 | |
| SCHEMBL7338189 | 0.77 | TDP1 (0.69) | PLAAT3PLAAT5PLAAT2PLAAT4L3MBTL1 | |
| SCHEMBL1663873 | 0.76 | CES2 (0.62) | CES2CES1PLAAT5PLAAT4FFAR1 | |
| SCHEMBL7219027 | 0.76 | CES2 (0.71) | CES2CES1L3MBTL1TDP1KDM4E | |
| SCHEMBL363773 | 0.75 | ALDH1A1 (0.65) | PLAAT3PLAAT5PLAAT2PLAAT4L3MBTL1 | |
| SCHEMBL169770 | 0.75 | FFAR1 (0.79) | L3MBTL1FFAR1TDP1LMNAALDH1A1 | |
| SCHEMBL6393031 | 0.75 | FFAR1 (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4L3MBTL1 | |
| SCHEMBL11179937 | 0.74 | TDP1 (0.61) | PLAAT3PLAAT5PLAAT2PLAAT4L3MBTL1 | |
| SCHEMBL23518790 | 0.74 | ALDH1A1 (0.61) | L3MBTL1FFAR1TDP1SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993022259-A1 | A PROCESS FOR PRODUCING 1,4-BISARYL-BUTANE-1,4-DIONES AND POLY(ARYLENE-BUTANE-1,4-DIONES) | NKT RESEARCH CENTER A/S (DK) | 1993-11-11 | — | — | WO | disclosed |